Major Depressive Disorder (MDD):

Major depressive disorder (MDD), also called clinical depression: MDD is a significant medical condition with serious emotional and physical problems, affecting mood, behavior, appetite, and sleep. We can feel as if life is not worth living. In DSM-5, MDD is diagnosed by 5/9 symptoms: sad mood, insomnia, feelings of guilt, decreased energy levels, decreased concentration, decreased appetite, decrease in pleasurable activities (anhedonia), increased or decreased psychomotor activity, and recurrent suicidal ideation/acts or self-harm/suicide attempt existing over a 2-week period. Most people with the disorder can learn to cope and function with medication, psychotherapy and/or other methods. Also see Depression